منابع مشابه
Lineages that cheat death: surviving the squeeze on range size.
Evolutionary lineages differ greatly in their net diversification rates, implying differences in rates of extinction and speciation. Lineages with a large average range size are commonly thought to have reduced extinction risk (although linking low extinction to high diversification has proved elusive). However, climate change cycles can dramatically reduce the geographic range size of even wid...
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Although, lying (bear false witness) is explicitly prohibited in the Decalogue and a focus of interest in philosophy and theology, more recently the behavioral and neural mechanisms of deception are gaining increasing attention from diverse fields especially economics, psychology, and neuroscience. Despite the considerable role of heredity in explaining individual differences in deceptive behav...
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Nuclear morphology and architecture are maintained by nucleoskeletal elements including, chromatin associated factors and nuclear lamina components both of which are involved in the regulation of chromatin 3D organization [1, 2]. As such, differentiated cells maintain a tissue-specific nuclear distribution of the euand heterochromatin and contain steady-state levels of nuclear lamina components...
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Antibodies against a vaccine vector render T cells more susceptible to HIV-1 infection, say Perreau et al. on page 2717. Their results may help explain the failure of a recent HIV vaccine trial. The HIV-1 vaccine used in Merck's STEP trial relied on a weakened form of a common cold virus, Adenovirus 5 (Ad5), to carry bits of HIV into the body. One worry about the Ad5 vector was that widespread ...
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Based on a massive transcription factor location analysis within a single cell type, in this issue Yan et al. find that the great majority of occupancies occur within dense clusters of up to 100 factors that almost invariably contain cohesins. Retention of cohesins at cluster sites during mitosis raises the possibility that they contribute to transcriptional memory during the cell cycle.
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2013
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2013.268243